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Turn up the power –pharmacological activation of mitochondrial biogenesis in mouse models

The oxidative phosphorylation (OXPHOS) system in mitochondria is responsible for the generation of the majority of cellular energy in the form of ATP. Patients with genetic OXPHOS disorders form the largest group of inborn errors of metabolism. Unfortunately, there is still a lack of efficient thera...

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Detalhes bibliográficos
Main Authors: Komen, J C, Thorburn, D R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976607/
https://ncbi.nlm.nih.gov/pubmed/24102298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12413
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