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Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

Cells die by a variety of mechanisms. Terminally differentiated cells such as neurones die in a variety of disorders, in part, via parthanatos, a process dependent on the activity of poly (ADP-ribose)-polymerase (PARP). Parthanatos does not require the mediation of caspases for its execution, but is...

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Detalhes bibliográficos
Main Authors: Fatokun, Amos A, Dawson, Valina L, Dawson, Ted M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976618/
https://ncbi.nlm.nih.gov/pubmed/24684389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12416
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