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Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?

Diabetic nephropathy (DN) is a progressive microvascular complication arising from diabetes. Within the kidney, the glomeruli, tubules, vessels and interstitium are disrupted, ultimately impairing renal function and leading to end-stage renal disease (ESRD). Current pharmacological therapies used in...

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Detalhes bibliográficos
Main Authors: Higgins, G C, Coughlan, M T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976613/
https://ncbi.nlm.nih.gov/pubmed/24720258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12503
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