Reduced Model Captures Mg(2+)-RNA Interaction Free Energy of Riboswitches

The stability of RNA tertiary structures depends heavily on Mg(2+). The Mg(2+)-RNA interaction free energy that stabilizes an RNA structure can be computed experimentally through fluorescence-based assays that measure Γ(2+), the number of excess Mg(2+) associated with an RNA molecule. Previous expli...

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Autori principali: Hayes, Ryan L., Noel, Jeffrey K., Whitford, Paul C., Mohanty, Udayan, Sanbonmatsu, Karissa Y., Onuchic, José N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2014
Soggetti:
Proteins and Nucleic Acids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976530/
https://ncbi.nlm.nih.gov/pubmed/24703312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.042
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