Mutations in the phosphoglucose isomerase gene can lead to marked alterations in cellular ATP levels in cultured fibroblasts exposed to simple nutrient shifts.

The generation of ATP in a hamster fibroblast mutant devoid of the enzyme phosphoglucose isomerase (PGI) has been studied and compared with that in the parental line, which is PGI+. Both cell lines could be maintained for 24 hr in hexose media devoid of L-glutamine. Under these conditions in mannose...

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Bibliografiska uppgifter
Huvudupphovsmän: Plesner, P, Ullrey, D B, Kalckar, H M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1985
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC397645/
https://ncbi.nlm.nih.gov/pubmed/3857613
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