लोड हो रहा है...
The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function
TMEM127 is an endosome-associated tumor suppressor gene in pheochromocytomas, neuroendocrine tumors that can co-occur with renal cell carcinomas (RCCs). TMEM127 loss leads to increased mTOR signaling. However, the spectrum of tumors with TMEM127 mutation and how TMEM127 and mTOR interact in tumorige...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976335/ https://ncbi.nlm.nih.gov/pubmed/24334765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt638 |
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