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Profile of vintafolide (EC145) and its use in the treatment of platinum-resistant ovarian cancer
OBJECTIVE: Our aim was to review the profile of vintafolide (EC145) and its rationale for use in platinum-resistant ovarian cancer. First we investigated the folate receptors (FRs), folate’s pathway into cells, and its expression in normal and cancerous cells, before detailing the mechanism of actio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976235/ https://ncbi.nlm.nih.gov/pubmed/24729732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJWH.S39696 |
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