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Targeted treatment of folate receptor-positive platinum-resistant ovarian cancer and companion diagnostics, with specific focus on vintafolide and etarfolatide

Among the gynecological malignancies, ovarian cancer is the leading cause of mortality in developed countries. Treatment of ovarian cancer is based on surgery integrated with chemotherapy. Platinum-based drugs (cisplatin and carboplatin) comprise the core of first-line chemotherapy for patients with...

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Detalhes bibliográficos
Main Authors: Serpe, Loredana, Gallicchio, Margherita, Canaparo, Roberto, Dosio, Franco
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917542/
https://ncbi.nlm.nih.gov/pubmed/24516337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S58374
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