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Dissecting the contributions of β-hairpin tyrosine pair to the folding and stability of long-lived human γD-crystallins

Ultraviolet-radiation-induced damage to and aggregation of human lens crystallin proteins are thought to be a significant pathway to age-related cataract. The aromatic residues within the duplicated Greek key domains of γ-and β-crystallins are the main ultraviolet absorbers and are susceptible to di...

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Hlavní autoři: Yang, Zaixing, Xia, Zhen, Huynh, Tien, King, Jonathan A., Zhou, Ruhong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976203/
https://ncbi.nlm.nih.gov/pubmed/24352614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3nr03782g
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