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Dissecting the contributions of β-hairpin tyrosine pair to the folding and stability of long-lived human γD-crystallins
Ultraviolet-radiation-induced damage to and aggregation of human lens crystallin proteins are thought to be a significant pathway to age-related cataract. The aromatic residues within the duplicated Greek key domains of γ-and β-crystallins are the main ultraviolet absorbers and are susceptible to di...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976203/ https://ncbi.nlm.nih.gov/pubmed/24352614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3nr03782g |
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