Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Associated Neoplasia

INTRODUCTION: WNT signaling pathway dysregulation is an important event in the pathogenesis of colorectal cancer (CRC) with APC mutations seen in more than 80% of sporadic CRC. However, such mutations in the WNT signaling pathway genes are rare in inflammatory bowel disease (IBD) associated neoplasi...

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Hauptverfasser: Dhir, Mashaal, Montgomery, Elizabeth A., Glöckner, Sabine C., Schuebel, Kornel E., Hooker, Craig M., Herman, James G., Baylin, Stephen B., Gearhart, Susan L., Ahuja, Nita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976145/
https://ncbi.nlm.nih.gov/pubmed/18716850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11605-008-0633-5
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