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Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
Mitochondrial DNA (mtDNA) contains unmethylated CpG motifs that exhibit immune stimulatory capacities. The aim of this study was to investigate whether mtDNA activates the Toll-like receptor 9 (TLR9)/nuclear factor-κB (NF-κB) pathway, thereby contributing to post-traumatic systemic inflammatory resp...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976143/ https://ncbi.nlm.nih.gov/pubmed/24535292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1650 |
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