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Optimized conditions for successful transfection of human endothelial cells with in vitro synthesized and modified mRNA for induction of protein expression

BACKGROUND: The induction of protein synthesis by exogenous delivery of coding synthetic mRNA in desired cells is an auspicious strategy in the fields of basic cell biology, regenerative medicine, treatment of diseases, and reprogramming of cells. Here, we produced modified messenger RNA (mRNA) with...

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Detalhes bibliográficos
Main Authors: Avci-Adali, Meltem, Behring, Andreas, Keller, Timea, Krajewski, Stefanie, Schlensak, Christian, Wendel, Hans Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975882/
https://ncbi.nlm.nih.gov/pubmed/24581116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-1611-8-8
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