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Neuregulin as a Heart Failure Therapy and Mediator of Reverse Remodeling
The beta isoform of Neuregulin-1 (NRG-1β), along with its receptors (ErbB2-4), is required for cardiac development. NRG-1β, as well as the ErbB2 and ErbB4 receptors are also essential for maintenance of adult heart function. These observations have led to its evaluation as a therapeutic for heart fa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975684/ https://ncbi.nlm.nih.gov/pubmed/24234399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11897-013-0176-2 |
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