Anti‐Remodeling and Anti‐Fibrotic Effects of the Neuregulin‐1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure

BACKGROUND: Neuregulin‐1β (NRG‐1β) is a growth factor critical for cardiac development and repair with therapeutic potential for heart failure. We previously showed that the glial growth factor 2 (GGF2) isoform of NRG‐1β improves cardiac function in rodents after myocardial infarction (MI), but its...

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Publicat a:J Am Heart Assoc
Autors principals: Galindo, Cristi L., Kasasbeh, Ehab, Murphy, Abigail, Ryzhov, Sergey, Lenihan, Sean, Ahmad, Farhaan A., Williams, Philip, Nunnally, Amy, Adcock, Jamie, Song, Yanna, Harrell, Frank E., Tran, Truc‐Linh, Parry, Tom J., Iaci, Jen, Ganguly, Anindita, Feoktistov, Igor, Stephenson, Matthew K., Caggiano, Anthony O., Sawyer, Douglas B., Cleator, John H.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323814/
https://ncbi.nlm.nih.gov/pubmed/25341890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000773
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