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Targeting epidermal lipids for treatment of Mendelian disorders of cornification

BACKGROUND: Inherited ichthyoses or Mendelian disorders of cornification (MeDOC) are clinically heterogeneous disorders with high unmet therapeutic needs, which are characterized by skin hyperkeratosis and scaling. Some MeDOC types are associated with defects of the epidermal lipid metabolism, resul...

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Bibliographic Details
Main Authors: Kiritsi, Dimitra, Schauer, Franziska, Wölfle, Ute, Valari, Manthoula, Bruckner-Tuderman, Leena, Has, Cristina, Happle, Rudolf
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975448/
https://ncbi.nlm.nih.gov/pubmed/24607067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-33
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