Targeting epidermal lipids for treatment of Mendelian disorders of cornification

BACKGROUND: Inherited ichthyoses or Mendelian disorders of cornification (MeDOC) are clinically heterogeneous disorders with high unmet therapeutic needs, which are characterized by skin hyperkeratosis and scaling. Some MeDOC types are associated with defects of the epidermal lipid metabolism, resul...

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Main Authors: Kiritsi, Dimitra, Schauer, Franziska, Wölfle, Ute, Valari, Manthoula, Bruckner-Tuderman, Leena, Has, Cristina, Happle, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975448/
https://ncbi.nlm.nih.gov/pubmed/24607067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-33
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