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A method for mapping intranuclear protein-DNA interactions and its application to a nuclease hypersensitive site.

We have devised a method for mapping sites on DNA within the nucleus that are protected against nuclease attack by interaction with bound protein or other factors. This "footprinting" method uses an end-labeled sequence-specific DNA probe, which is annealed to the DNA from nuclear digests...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jackson, P D, Felsenfeld, G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1985
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC397544/
https://ncbi.nlm.nih.gov/pubmed/3857580
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