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The all-or-none role of innervation in expression of apamin receptor and of apamin-sensitive Ca2+-activated K+ channel in mammalian skeletal muscle.

The long-lasting after-hyperpolarization(s) (AHP) that follows the action potential in rat myotubes differentiated in culture is due to Ca2+-activated K+ channels. These channels have the property to be specifically blocked by the bee venom toxin apamin at low concentrations. Apamin has been used in...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Schmid-Antomarchi, H, Renaud, J F, Romey, G, Hugues, M, Schmid, A, Lazdunski, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397518/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2580309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.7.2188
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