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STRIDER: Sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction – a protocol for a systematic review with individual participant data and aggregate data meta-analysis and trial sequential analysis

BACKGROUND: In pregnancies complicated by early-onset extreme fetal growth restriction, there is a high risk of preterm birth and an overall dismal fetal prognosis. Sildenafil has been suggested to improve this prognosis. The first aim of this review is to assess whether sildenafil benefits or harms...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ganzevoort, Wessel, Alfirevic, Zarko, von Dadelszen, Peter, Kenny, Louise, Papageorghiou, Aris, van Wassenaer-Leemhuis, Aleid, Gluud, Christian, Mol, Ben Willem, Baker, Philip N
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975177/
https://ncbi.nlm.nih.gov/pubmed/24618418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-4053-3-23
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