Prenatal Use of Sildenafil in Fetal Growth Restriction and Its Effect on Neonatal Tissue Oxygenation—A Retrospective Analysis of Hemodynamic Data From Participants of the Dutch STRIDER Trial

Objective: Sildenafil is under investigation as a potential agent to improve uteroplacental perfusion in fetal growth restriction (FGR). However, the STRIDER RCT was halted after interim analysis due to futility and higher rates of persistent pulmonary hypertension and mortality in sildenafil-expose...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pediatr
Hauptverfasser: Terstappen, Fieke, Richter, Anne E., Lely, A. Titia, Hoebeek, Freek E., Elvan-Taspinar, Ayten, Bos, Arend F., Ganzevoort, Wessel, Pels, Anouk, Lemmers, Petra M., Kooi, Elisabeth M. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pediatrics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744464/
https://ncbi.nlm.nih.gov/pubmed/33344386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.595693
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