Mice Lacking Selenoprotein P and Selenocysteine Lyase Exhibit Severe Neurological Dysfunction, Neurodegeneration, and Audiogenic Seizures

Selenoproteins are a unique family of proteins, characterized by the co-translational incorporation of selenium as selenocysteine, which play key roles in antioxidant defense. Among selenoproteins, selenoprotein P (Sepp1) is particularly distinctive due to the fact that it contains multiple selenocy...

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Detalles Bibliográficos
Autores principales: Byrns, China N., Pitts, Matthew W., Gilman, Christy A., Hashimoto, Ann C., Berry, Marla J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975015/
https://ncbi.nlm.nih.gov/pubmed/24519931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.540682
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