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Absence of Selenoprotein P but not Selenocysteine Lyase Results in Severe Neurological Dysfunction

Dietary selenium restriction in mammals causes bodily selenium to be preferentially retained in the brain relative to other organs. Almost all of the known selenoproteins are found in brain, where expression is facilitated by selenocysteine-laden selenoprotein P. The brain also expresses selenocyste...

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Detalhes bibliográficos
Main Authors: Raman, Arjun V., Pitts, Matthew W., Seyedali, Ali, Hashimoto, Ann C., Seale, Lucia A., Bellinger, Frederick P., Berry, Marla J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389215/
https://ncbi.nlm.nih.gov/pubmed/22487427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2012.00794.x
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