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Furanocoumarins Are a Novel Class of Modulators for the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channel

Furanocoumarin imperatorin is the major active component of Angelica dahurica root extracts, widely used in traditional medicine to treat headache, toothache, and orbital eye pain. In this study, we investigated the mechanisms that may underlie the pain-relieving effects of the compound. We found th...

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Hlavní autoři: Chen, Xingjuan, Sun, Weiyang, Gianaris, Nicholas G., Riley, Ashley M., Cummins, Theodore R., Fehrenbacher, Jill C., Obukhov, Alexander G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975010/
https://ncbi.nlm.nih.gov/pubmed/24569998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536862
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