Furanocoumarins Are a Novel Class of Modulators for the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channel

Furanocoumarin imperatorin is the major active component of Angelica dahurica root extracts, widely used in traditional medicine to treat headache, toothache, and orbital eye pain. In this study, we investigated the mechanisms that may underlie the pain-relieving effects of the compound. We found th...

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Autores principales: Chen, Xingjuan, Sun, Weiyang, Gianaris, Nicholas G., Riley, Ashley M., Cummins, Theodore R., Fehrenbacher, Jill C., Obukhov, Alexander G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975010/
https://ncbi.nlm.nih.gov/pubmed/24569998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536862
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