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Myocilin Regulates Cell Proliferation and Survival

Myocilin, a causative gene for open angle glaucoma, encodes a secreted glycoprotein with poorly understood functions. To gain insight into its functions, we produced a stably transfected HEK293 cell line expressing myocilin under an inducible promoter and compared gene expression profiles between my...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joe, Myung Kuk, Kwon, Heung Sun, Cojocaru, Radu, Tomarev, Stanislav I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974985/
https://ncbi.nlm.nih.gov/pubmed/24563482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.547091
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