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A Novel Mechanism by Which Tissue Transglutaminase Activates Signaling Events That Promote Cell Survival

Tissue transglutaminase (tTG) functions as a GTPase and an acyl transferase that catalyzes the formation of protein cross-links. tTG expression is frequently up-regulated in human cancer, where it has been implicated in various aspects of cancer progression, including cell survival and chemo-resista...

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Autori principali: Boroughs, Lindsey K., Antonyak, Marc A., Cerione, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974982/
https://ncbi.nlm.nih.gov/pubmed/24569994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464693
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