N-terminal Isoforms of the Large-conductance Ca(2+)-activated K(+) Channel Are Differentially Modulated by the Auxiliary β1-Subunit

The large-conductance Ca(2+)-activated K(+) (BK(Ca)) channel is essential for maintaining the membrane in a hyperpolarized state, thereby regulating neuronal excitability, smooth muscle contraction, and secretion. The BK(Ca) α-subunit has three predicted initiation codons that generate proteins with...

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Autori principali: Lorca, Ramón A., Stamnes, Susan J., Pillai, Meghan K., Hsiao, Jordy J., Wright, Michael E., England, Sarah K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974980/
https://ncbi.nlm.nih.gov/pubmed/24569989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521526
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