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N-terminal Isoforms of the Large-conductance Ca(2+)-activated K(+) Channel Are Differentially Modulated by the Auxiliary β1-Subunit
The large-conductance Ca(2+)-activated K(+) (BK(Ca)) channel is essential for maintaining the membrane in a hyperpolarized state, thereby regulating neuronal excitability, smooth muscle contraction, and secretion. The BK(Ca) α-subunit has three predicted initiation codons that generate proteins with...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974980/ https://ncbi.nlm.nih.gov/pubmed/24569989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521526 |
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