IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion

Interferon-induced transmembrane proteins (IFITMs) inhibit infection of diverse enveloped viruses, including the influenza A virus (IAV) which is thought to enter from late endosomes. Recent evidence suggests that IFITMs block virus hemifusion (lipid mixing in the absence of viral content release) b...

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Dettagli Bibliografici
Autori principali: Desai, Tanay M., Marin, Mariana, Chin, Christopher R., Savidis, George, Brass, Abraham L., Melikyan, Gregory B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974867/
https://ncbi.nlm.nih.gov/pubmed/24699674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004048
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