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Inactivation of Genes for Antigenic Variation in the Relapsing Fever Spirochete Borrelia hermsii Reduces Infectivity in Mice and Transmission by Ticks

Borrelia hermsii, a causative agent of relapsing fever of humans in western North America, is maintained in enzootic cycles that include small mammals and the tick vector Ornithodoros hermsi. In mammals, the spirochetes repeatedly evade the host’s acquired immune response by undergoing antigenic var...

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Detalhes bibliográficos
Main Authors: Raffel, Sandra J., Battisti, James M., Fischer, Robert J., Schwan, Tom G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974855/
https://ncbi.nlm.nih.gov/pubmed/24699793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004056
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