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Inactivation of genes for antigenic variation in the relapsing fever spirochete Borrelia hermsii reduces infectivity in mice and transmission by ticks.

Borrelia hermsii, a causative agent of relapsing fever of humans in western North America, is maintained in enzootic cycles that include small mammals and the tick vector Ornithodoros hermsi. In mammals, the spirochetes repeatedly evade the host's acquired immune response by undergoing antigenic var...

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Bibliografiske detaljer
Principais autores: Sandra J Raffel, James M Battisti, Robert J Fischer, Tom G Schwan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-04-01
Serier:PLoS Pathogens
Online adgang:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004056&type=printable
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