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A Random Sequential Mechanism of Aminoglycoside Acetylation by Mycobacterium tuberculosis Eis Protein

An important cause of bacterial resistance to aminoglycoside antibiotics is the enzymatic acetylation of their amino groups by acetyltransferases, which abolishes their binding to and inhibition of the bacterial ribosome. Enhanced intracellular survival (Eis) protein from Mycobacterium tuberculosis...

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Bibliografski detalji
Glavni autori: Tsodikov, Oleg V., Green, Keith D., Garneau-Tsodikova, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974725/
https://ncbi.nlm.nih.gov/pubmed/24699000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092370
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