SDA, a DNA Aptamer Inhibiting E- and P-Selectin Mediated Adhesion of Cancer and Leukemia Cells, the First and Pivotal Step in Transendothelial Migration during Metastasis Formation

Endothelial (E-) and platelet (P-) selectin mediated adhesion of tumor cells to vascular endothelium is a pivotal step of hematogenous metastasis formation. Recent studies have demonstrated that selectin deficiency significantly reduces metastasis formation in vivo. We selected an E- and P-Selectin...

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Detalhes bibliográficos
Main Authors: Faryammanesh, Rassa, Lange, Tobias, Magbanua, Eileen, Haas, Sina, Meyer, Cindy, Wicklein, Daniel, Schumacher, Udo, Hahn, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974700/
https://ncbi.nlm.nih.gov/pubmed/24699049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093173
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