A LINE-1 Insertion in DLX6 Is Responsible for Cleft Palate and Mandibular Abnormalities in a Canine Model of Pierre Robin Sequence

Cleft palate (CP) is one of the most commonly occurring craniofacial birth defects in humans. In order to study cleft palate in a naturally occurring model system, we utilized the Nova Scotia Duck Tolling Retriever (NSDTR) dog breed. Micro-computed tomography analysis of CP NSDTR craniofacial struct...

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Détails bibliographiques
Auteurs principaux: Wolf, Zena T., Leslie, Elizabeth J., Arzi, Boaz, Jayashankar, Kartika, Karmi, Nili, Jia, Zhonglin, Rowland, Douglas J., Young, Amy, Safra, Noa, Sliskovic, Saundra, Murray, Jeffrey C., Wade, Claire M., Bannasch, Danika L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974639/
https://ncbi.nlm.nih.gov/pubmed/24699068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004257
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