A LINE-1 Insertion in DLX6 Is Responsible for Cleft Palate and Mandibular Abnormalities in a Canine Model of Pierre Robin Sequence

Cleft palate (CP) is one of the most commonly occurring craniofacial birth defects in humans. In order to study cleft palate in a naturally occurring model system, we utilized the Nova Scotia Duck Tolling Retriever (NSDTR) dog breed. Micro-computed tomography analysis of CP NSDTR craniofacial struct...

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Main Authors: Wolf, Zena T., Leslie, Elizabeth J., Arzi, Boaz, Jayashankar, Kartika, Karmi, Nili, Jia, Zhonglin, Rowland, Douglas J., Young, Amy, Safra, Noa, Sliskovic, Saundra, Murray, Jeffrey C., Wade, Claire M., Bannasch, Danika L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974639/
https://ncbi.nlm.nih.gov/pubmed/24699068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004257
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