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Targeted Delivery of Ubiquitin-Conjugated BH3 Peptide-Based Mcl-1 Inhibitors into Cancer Cells

[Image: see text] BH3 peptides are key mediators of apoptosis and have served as the lead structures for the development of anticancer therapeutics. Previously, we reported the application of a simple cysteine-based side chain cross-linking chemistry to NoxaBH3 peptides that led to the generation of...

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Detalhes bibliográficos
Main Authors: Muppidi, Avinash, Doi, Kenichiro, Edwardraja, Selvakumar, Pulavarti, Surya V. S. R. K., Szyperski, Thomas, Wang, Hong-Gang, Lin, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974624/
https://ncbi.nlm.nih.gov/pubmed/24410055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc4005574
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