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Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism

The natural bases of nucleic acids have a strong preference for one tautomer form, guaranteeing fidelity in their hydrogen bonding potential. However, base pairs observed in recent crystal structures of polymerases and ribosomes are best explained by an alternative base tautomer, leading to the form...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Westhof, Eric, Yusupov, Marat, Yusupova, Gulnara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Faculty of 1000 Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974571/
https://ncbi.nlm.nih.gov/pubmed/24765524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P6-19
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