Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding.

Tumor-promoting phorbol esters induce ornithine decarboxylase (ODCase) activity and reduce epidermal growth factor (EGF) binding in rat tracheal epithelial 2C5 cells. Phorbol esters activate protein kinase C by interacting at the same site as sn-1,2-diacylglycerols, the presumed physiological regula...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Jetten, A M, Ganong, B R, Vandenbark, G R, Shirley, J E, Bell, R M
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1985
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3157191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.7.1941
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