Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding.

Tumor-promoting phorbol esters induce ornithine decarboxylase (ODCase) activity and reduce epidermal growth factor (EGF) binding in rat tracheal epithelial 2C5 cells. Phorbol esters activate protein kinase C by interacting at the same site as sn-1,2-diacylglycerols, the presumed physiological regula...

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Main Authors: Jetten, A M, Ganong, B R, Vandenbark, G R, Shirley, J E, Bell, R M
Formato: Artigo
Idioma:Inglês
Publicado: 1985
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC397453/
https://ncbi.nlm.nih.gov/pubmed/3157191
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