Studies on angiotensin II and analogs: impact of substitution in position 8 on conformation and activity.

Affinity, residual agonist activity, and inhibitor properties of a series of angiotensin II analogs modified at the COOH-terminal position (X8-substituted peptides) have been probed for structure/conformation-biological activity relationships. The results emphasize (i) the large impact that subtle c...

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Main Authors: Aumelas, A, Sakarellos, C, Lintner, K, Fermandjian, S, Khosla, M C, Smeby, R R, Bumpus, F M
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC397434/
https://ncbi.nlm.nih.gov/pubmed/3856867
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