Studies on angiotensin II and analogs: impact of substitution in position 8 on conformation and activity.

Affinity, residual agonist activity, and inhibitor properties of a series of angiotensin II analogs modified at the COOH-terminal position (X8-substituted peptides) have been probed for structure/conformation-biological activity relationships. The results emphasize (i) the large impact that subtle c...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Aumelas, A, Sakarellos, C, Lintner, K, Fermandjian, S, Khosla, M C, Smeby, R R, Bumpus, F M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397434/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.7.1881
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