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Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori

Half the world's population is chronically infected with Helicobacter pylori(1), causing gastritis, ulcers and increased incidence of gastric adenocarcinoma(2). Its proton-gated inner-membrane urea channel, HpUreI, is essential for survival in the acidic environment of the stomach(3). The chann...

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Detalhes bibliográficos
Main Authors: Strugatsky, David, McNulty, Reginald, Munson, Keith, Chen, Chiung-Kuang, Soltis, S. Michael, Sachs, George, Luecke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974264/
https://ncbi.nlm.nih.gov/pubmed/23222544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11684
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