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Mechanisms of molecular transport through the urea channel of Helicobacter pylori

Helicobacter pylori survival in acidic environments relies on cytoplasmic hydrolysis of gastric urea into ammonia and carbon dioxide, which buffer the pathogen’s periplasm. Urea uptake is greatly enhanced and regulated by HpUreI, a proton-gated inner membrane channel protein essential for gastric su...

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Библиографические подробности
Главные авторы: McNulty, Reginald, Ulmschneider, Jakob P., Luecke, Hartmut, Ulmschneider, Martin B.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863980/
https://ncbi.nlm.nih.gov/pubmed/24305683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3900
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