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Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth

Receptor tyrosine kinases of the Eph family are up-regulated in different types of cancer. EphB4 and its ligand ephrin-B2 have been linked to breast cancer, but little is known about how this receptor–ligand complex may contribute to oncogenesis. The Eph receptors transmit forward signals via their...

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Autori principali: Noren, Nicole K., Lu, Mark, Freeman, Andrew L., Koolpe, Mitchell, Pasquale, Elena B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC397426/
https://ncbi.nlm.nih.gov/pubmed/15067119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401381101
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