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Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition–cyclization strategy: Synthesis of (–)-flustramine B

Pyrroloindoline and bispyrroloindoline are a subclass of alkaloid structural motifs that commonly exhibit biological activity. An enantioselective organocatalytic approach to the synthesis of pyrroloindoline architecture is described. The addition–cyclization of tryptamines with α,β-unsaturated alde...

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Библиографические подробности
Главные авторы: Austin, Joel F., Kim, Sung-Gon, Sinz, Christopher J., Xiao, Wen-Jing, MacMillan, David W. C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC397409/
https://ncbi.nlm.nih.gov/pubmed/15067109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308177101
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