Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammation

BACKGROUND: Nuclear factor-erythroid 2-related factor 2 (Nrf2) has emerged as a novel target for the prevention of colorectal cancer (CRC). Many chemopreventive compounds associated with Nrf2 activation are effective in preclinical systems and many on-going clinical trials are showing promising find...

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Main Authors: Yang, Yang, Cai, Xueting, Yang, Jie, Sun, Xiaoyan, Hu, Chunping, Yan, Zhanpeng, Xu, Xiaojun, Lu, Wuguang, Wang, Xiaoning, Cao, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973863/
https://ncbi.nlm.nih.gov/pubmed/24602443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-48
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