PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Mammalian circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), and current dogma holds that the SCN is required for the expression of circadian rhythms in peripheral tissues. Using a PERIOD2::LUCIFERASE fusion protein as a real-time reporter of circadian dynamics in mice, we report...

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Bibliographic Details
Main Authors: Yoo, Seung-Hee, Yamazaki, Shin, Lowrey, Phillip L., Shimomura, Kazuhiro, Ko, Caroline H., Buhr, Ethan D., Siepka, Sandra M., Hong, Hee-Kyung, Oh, Won Jun, Yoo, Ook Joon, Menaker, Michael, Takahashi, Joseph S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC397382/
https://ncbi.nlm.nih.gov/pubmed/14963227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308709101
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