Mu and kappa opioids inhibit transmitter release by different mechanisms.
The actions of various opioids were examined on calcium action potentials in the cell somata of guinea pig myenteric neurones and on the release of acetylcholine at synapses onto these cells. The opioids morphine, normorphine, and [D-Ala2, MePhe4, Met5(O)]enkephalin-ol caused membrane hyperpolarizat...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1985
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2984670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.6.1860 |
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