A Niche-Like Culture System Allowing the Maintenance of Primary Human Acute Myeloid Leukemia-Initiating Cells: A New Tool to Decipher Their Chemoresistance and Self-Renewal Mechanisms

Acute myeloid leukemia-initiating cells (LICs) are responsible for the emergence of leukemia and relapse after chemotherapy. Despite their identification more than 15 years ago, our understanding of the mechanisms responsible for their self-renewal activity and their chemoresistance remains poor. Th...

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Bibliografiska uppgifter
Huvudupphovsmän: Griessinger, Emmanuel, Anjos-Afonso, Fernando, Pizzitola, Irene, Rouault-Pierre, Kevin, Vargaftig, Jacques, Taussig, David, Gribben, John, Lassailly, François, Bonnet, Dominique
Materialtyp: Artigo
Språk:Inglês
Publicerad: AlphaMed Press 2014
Ämnen:
Cancer Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973718/
https://ncbi.nlm.nih.gov/pubmed/24493855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0166
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