A Niche-Like Culture System Allowing the Maintenance of Primary Human Acute Myeloid Leukemia-Initiating Cells: A New Tool to Decipher Their Chemoresistance and Self-Renewal Mechanisms

Acute myeloid leukemia-initiating cells (LICs) are responsible for the emergence of leukemia and relapse after chemotherapy. Despite their identification more than 15 years ago, our understanding of the mechanisms responsible for their self-renewal activity and their chemoresistance remains poor. Th...

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Détails bibliographiques
Auteurs principaux: Griessinger, Emmanuel, Anjos-Afonso, Fernando, Pizzitola, Irene, Rouault-Pierre, Kevin, Vargaftig, Jacques, Taussig, David, Gribben, John, Lassailly, François, Bonnet, Dominique
Format: Artigo
Langue:Inglês
Publié: AlphaMed Press 2014
Sujets:
Cancer Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973718/
https://ncbi.nlm.nih.gov/pubmed/24493855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0166
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