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ATP6V0C Knockdown in Neuroblastoma Cells Alters Autophagy-Lysosome Pathway Function and Metabolism of Proteins that Accumulate in Neurodegenerative Disease

ATP6V0C is the bafilomycin A1-binding subunit of vacuolar ATPase, an enzyme complex that critically regulates vesicular acidification. We and others have shown previously that bafilomycin A1 regulates cell viability, autophagic flux and metabolism of proteins that accumulate in neurodegenerative dis...

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Detaylı Bibliyografya
Asıl Yazarlar: Mangieri, Leandra R., Mader, Burton J., Thomas, Cailin E., Taylor, Charles A., Luker, Austin M., Tse, Tonia E., Huisingh, Carrie, Shacka, John J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973706/
https://ncbi.nlm.nih.gov/pubmed/24695574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093257
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